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primary human bronchial epithelial cells hbepc  (PromoCell)


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    PromoCell primary human bronchial epithelial cells hbepc
    Primary Human Bronchial Epithelial Cells Hbepc, supplied by PromoCell, used in various techniques. Bioz Stars score: 95/100, based on 123 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 95 stars, based on 123 article reviews
    primary human bronchial epithelial cells hbepc - by Bioz Stars, 2026-02
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    HDM d oes not have mutagenic effects in human and mouse lung epithelial cell lines i n v itro . A) Dose-response curves of HDM treatment in BEAS-2B and LLC cells. Cell viability is shown relative to vehicle control (PBS; % of control). Calculated IC 50 values are indicated. B) Experimental setup for HDM exposure and duplex sequencing. BEAS-2B and LLC cells were treated with either HDM (200 µg/mL for BEAS-2B; 400 µg/mL for LLC) or vehicle (VEH; PBS), expanded across multiple passages, and subsequently subjected to genomic sequencing. C) Comparison of mutational burden between samples treated with either HDM (purple) or VEH (blue), shown as somatic mutations per megabase (Mb) of coding DNA. D) Mutational spectra of BEAS-2B and LLC cells treated with HDM compared to VEH controls. Mutations are classified into the six base substitution categories and displayed in SBS96 format. The experiments were performed in triplicate (A) or singlicate (B-D).

    Journal: Neoplasia (New York, N.Y.)

    Article Title: Multi-omics profiling reveals microenvironmental remodeling as a key driver of house dust mite-induced lung cancer progression

    doi: 10.1016/j.neo.2026.101275

    Figure Lengend Snippet: HDM d oes not have mutagenic effects in human and mouse lung epithelial cell lines i n v itro . A) Dose-response curves of HDM treatment in BEAS-2B and LLC cells. Cell viability is shown relative to vehicle control (PBS; % of control). Calculated IC 50 values are indicated. B) Experimental setup for HDM exposure and duplex sequencing. BEAS-2B and LLC cells were treated with either HDM (200 µg/mL for BEAS-2B; 400 µg/mL for LLC) or vehicle (VEH; PBS), expanded across multiple passages, and subsequently subjected to genomic sequencing. C) Comparison of mutational burden between samples treated with either HDM (purple) or VEH (blue), shown as somatic mutations per megabase (Mb) of coding DNA. D) Mutational spectra of BEAS-2B and LLC cells treated with HDM compared to VEH controls. Mutations are classified into the six base substitution categories and displayed in SBS96 format. The experiments were performed in triplicate (A) or singlicate (B-D).

    Article Snippet: Human bronchial epithelial cells (BEAS-2B) were purchased in 2018 from ATCC (Cat. No CRL-9609).

    Techniques: Control, Sequencing, Genomic Sequencing, Comparison